[REF] UBP-C00620C, UBP-C00616C
[Specification] 20 tests/kit (Liquid), 16 tests/kit (Lyophilized)
[Intended Use]
UltraDx HPV 15 Genotyping Detection Kit is intended for the in-vitro qualitative detection of nucleic acids of 15 HR-HPV types (16, 18, 31, 33, 35, 39, 45, 51, 52, 53, 56, 58, 59, 66, 68) in cervical exfoliated cells and genotyping for 15 HPV types.
Human Papilloma virus (HPV), belonging to the Papillomaviridae family, is a small, circular, non-enveloped, double-stranded DNA virus, with a genome length of about 8,000 base pairs (bp). HPV infection is very common in women. About 80% of women have been infected with HPV in their lifetime, and 90% of them can be naturally cleared within one to two years. Based on their oncogenic potential, HPVs are classified as low-risk, associated with benign warts or epithelial lesions, or high-risk, that can cause oropharyngeal and anogenital malignancies, including cancers of the cervix, vulva, vagina, penis, and anus. High-risk HPV (hr-HPV) types are responsible for ~5% of all human cancers and are detected in 99.7% of cervical cancer cases, the fourth most common cancer in women, accounting for 7.5% of all cancer-associated deaths in women worldwide per year.
This kit uses specific primers and fluorescent probes for 15 types of human papillomavirus, using polymerase chain reaction (PCR) and Taqman technology to detect specific DNA fragments for 15 human papillomavirus types, respectively. The PCR amplification reaction system of this kit also contains the Uracil-N-Glycosylase and can selectively break the uracil glycosiside bond in the PCR fragment containing dUTP, effectively reducing false positives due to contamination of the PCR product.
HIGH SENSITIVITY
·No cross-reactivity with the common reproductive tractpathogens, and the results are more accurate
HIGH SPECIFICITY
·Ensures excellent sensitivity 100 copies/mL
SELF-SAMPLING OPTION
·Can be used with healthcare worker-instructed self-collected vaginal specimens/cervical specimens/urine
CONTAMINATION PREVENTION
·Ready-to-Use Master Mix contains Uracil-DNA
·glycosylase (UNG) and dUTPs eliminating possible carryover contamination
MULTIPLE REAGENT TYPES
·Lyophilized and liquid.(Convenient and economical)
HIGHLY COMPATIBLE
·Compatible with a wide range of real-time PCR devices
·Multiple extraction methods for option: magnetic bead extraction, membrane column, sample release reagent.
Cervical swabs,Urine
Applied Biosystems 7500 Real-Time PCR Systems, Bio-Rad CFX96 Real-Time PCR System, UltraDx eQ9600 Real Time qPCR System etc.
